Pns1200274 153..159
نویسنده
چکیده
Genetic susceptibility testing for common complex disease is a practice that is currently in clinical use. There are two types of gene mutations, and therefore, two varieties of genotype testing: deterministic and susceptibility. As the term suggests, deterministic genes determine whether or not a person will develop a given trait in Mendelian fashion, such as Huntington’s disease. Genotype screening for such deterministic mutations has existed for decades, and is commonly used in routine medical practice. In recent years, the sequencing of the human genome has identified several ‘susceptibility genes’ or genes with incomplete penetrance. Mutations in these genes may increase disease susceptibility, but are not causative for disease. Genetic susceptibility testing allows unaffected individuals to obtain risk information for a variety of common complex diseases and health conditions including Alzheimer’s disease (AD), CVD, cancer and diabetes. The availability of genetic susceptibility testing has increased over the past decade, and several studies are now focusing on the impact that genetic testing has on health and other lifestyle behaviours related to nutrition. The aim of this paper is to review the literature and evaluate what, if any, impact genetic risk assessment has on behaviours related to nutrition and physical activity. This paper summarises seven clinical studies that evaluated the impact of disclosing genetic risk information for disease on nutrition-related health behaviour changes. Of these seven studies, only three studies reported that health behaviour change was influenced by genotype disclosure.
منابع مشابه
Symmetric Spectra
Introduction 150 Organization 152 Acknowledgments 152 1. Symmetric spectra 153 1.1. Simplicial sets 153 1.2. Symmetric spectra 154 1.3. Simplicial structure on Sp 156 1.4. Symmetric Ω-spectra 158 2. The smash product of symmetric spectra 159 2.1. Symmetric sequences 159 2.2. Symmetric spectra 162 2.3. The ordinary category of spectra 165 3. Stable homotopy theory of symmetric spectra 165 3.1. S...
متن کاملEffects of Stress on Learning and Memory
Effects of Stress on Learning and Memory in Humans 153 Introduction 153 The Conceptual and Anatomical Basis in Humans of Learning and Memory 154 Mechanisms Behind the Relationship Between Stress, Learning, and Memory 155 Vulnerability of Human Memory 156 Encoding, Consolidation, and Retrieval in Stressful, and Emotionally Loaded Situations 156 Summary 157 Effects of Stress on Learning and Memor...
متن کاملSports Med 2007; 37 (2): 145-168
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 146 1. Morphological Adaptations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 146 1.1 Changes in Whole-Muscle Size . . . . . . . . . . . . . . . . . ....
متن کاملInternational Price Levels and Purchasing Power Parities
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1. Background data and methods . . . . . . . . . . . . . . . . . . . II. PPPs and real expenditures in 1980 . . . . . . . . . . . . . . . . 111. Patterns of relative prices in OECD countries . . . . . . . . . . . . IV. Comparative price levels and real per capita GDP . . . . . . . . . V. Price levels, purchasing power pa...
متن کاملCancer and facial disfigurement: reducing survivors' stigma in social interaction.
Patients with orbital and periorbital cancer expect to be cured or survive for several years after their malignancy is detected and surgically removed. However, despite advancements in reconstructive surgery, survivors often remain facially disfigured and spend significant portions of their lives dealing with stigma, a mark of social disgrace. Although research remains limited, this article des...
متن کامل